Chemists from Ruđer Bošković Institute develop new asymmetric organocatalytic method

Researchers from the Laboratory for Biomimetic Chemistry of the Ruđer Bošković Institute Mateja Matišić and Matija Gredičak have published a paper in Chemical Communications, in which they describe a new protocol for synthesising a type of optically pure core structures of a number of biologically active compounds. This protocol is much greener and more effective than many methods in use today and has extremely high potential for application in the pharmaceutical industry.

The developed protocol is the result of research carried out under the project IP-2018-01-4053 “New Strategies for the Synthesis of Tetrasubstituted Chiral Centers: Asymmetric Counteranion-Directed Catalysis (NSYNC-ACDC)”, while the first author of the paper Mateja Matišić is a doctoral student employed through the Foundation’s “Young Researchers’ Career Development Project” (DOK-2018-01).

You can read more about these results in RBI’s press release.

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